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To begin with, GLP-1 is secreted by L cells in the lower intestine, and its secretory stimuli include nutrients, the gut microbiota itself, and metabolites of the gut microbiota, such as short-chain fatty acids 47,48

Diabetes 61:187196 Sakar Y, Meddah B, Faouzi MA, Cherrah Y, Bado A, Ducroc R (2010) Metformin-induced regulation of the intestinal D-glucose transporters

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