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A large study of 2,000 obese adults found that participants using semaglutide combined with diet and exercise lost up to 15-20% of their body weight after 68 weeks

Ogawa R, Streiff MB, Bugayenko A, et al

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In what Lilly said was a key secondary endpoint, 59.6% of participants taking the 36 mg dose of orforglipron lost at least 10% of their body weight, while 39.6% lost at least 15% of their body weight

952103, GLIOMATCH no