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& Galie, P

Kidney Dysfunction: While the kidneys do not directly excrete vitamin B12 efficiently, impaired renal function may lead to elevated serum B12 levels by reducing the clearance of B12-binding proteins or altering their metabolism, thereby contributing to B12 accumulation 8

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Pharmacokinetically, BPC-157 has a relatively short plasma half-life estimated at 10-15 minutes when administered parenterally, though its tissue-level effects persist far longer due to receptor-level interactions and growth factor cascading

2012;5(Spec Issue):137-140

This is an opportunity to find a new way forward to advance medical innovation by leveraging real-world data, instead of relying on expensive and time-consuming trials whose limitations are growing more and more apparent