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Targeted induction of ceramide degradation leads to improved systemic metabolism and reduced hepatic steatosis
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10.1210/endo.138.10.5270 Endocrinology 39 LennoxR.FlattP
Injectable administration is hypothesized to provide systemic distribution, but human pharmacokinetic data for this route does not exist
Ultimately, CPT2 on the inner mitochondrial membrane converts LCACs to free carnitine and long-chain acyl-CoA
Abstract A growing appreciation of the overlapping neuroendocrine mechanisms controlling energy balance has highlighted combination therapies as a promising strategy to enhance sustained weight loss
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