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Interestingly, the aryl hydrocarbon receptor (AhR) of the tryptophan-kynurenine pathway serves as a critically important mediator between tryptophan metabolism, immune reactions, and tissue homeostasis (4143), and several kynurenine metabolites have been associated with fatigue (44, 45)

Faced with the threat of chronic conditions from weight gain, Thomas connected with a provider who helped him find more beneficial exercise methods for his life off the field

qRTPCR Total RNA was extracted with TRIzol (Invitrogen, Cat#15596026)

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