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The NRF2-dependent effect was identified through the antioxidative response element in target gene loci, while NRF2-independent effects act through DNA 5hmC modifications via the regulation of the metabolite L2HG

BMJ Open Ophthalmol

IV therapy pricing also varies by the goal of the treatment rather than just the ingredients

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Provides a comprehensive summary of the PTMs exerted by various enzymes on ferroptosis-related proteins, elucidating their mechanisms and potential associations with ferroptosis-related diseases