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Severe dehydration can lead to acute kidney injury, which is specifically mentioned in FDA warnings for these medications

doi: 10.1038/s41581-021-00393-8 2 ZhengYLeySHHuFB

S., Bai C., Jones P

Traumatic endplate damage also causes necrotic cell death 13 and the release of intracellular contents, including many pro-inflammatory compounds known as damage-associated molecular patterns (DAMPs)

(1994, Journal of Clinical Endocrinology and Metabolism) reporting mean GH peaks in the range of 40 to 90 ng/mL depending on age and sex of subjects