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This is general laboratory handling information for research use only, not guidance for any person

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While the concentration of active peptides in shampoo formulations is typically lower than in dedicated serums, daily use provides consistent exposure and can complement other interventions

doi: 10.1038/nrm3890 300 WangFChenFFGaoWBWangHYZhaoNWXuMet al

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Results We describe parenteral administration of OHCbl using a subcutaneous catheter together with a portable infusion pump in a home therapy setting in four pediatric patients with remethylation disorders, two patients with cblC, one patient with cblG, and one patient with cblE deficiency, in whom intramuscular injections were not or no longer feasible