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Diabetologia 29:4654 Deacon CF, Danielsen P, Klarskov L, Olesen M, Holst JJ (2001) Dipeptidyl peptidase IV inhibition reduces the degradation and clearance of GIP and potentiates its insulinotropic and antihyperglycemic effects in anesthetized pigs

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The most prominent reason is the limited dietary sources of vitamin B12, which is primarily found in animal products such as meat, fish, dairy, and eggs