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At week 12, women in the collagen group displayed significantly improved skin scores for wrinkle, elasticity, hydration, radiance, and firmness compared with placebo control values (via VISIA skin analysis system, Cutometer , and Skin Quality Visual Analogue Scale)

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Final Thoughts 5-Amino-1MQ's adipose tissue research thread is the most-developed application area for this small-molecule NNMT inhibitor, anchored on the landmark 2014 Kraus Nature paper that established the adipose-NNMT connection

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We have previously demonstrated an increased nicotinamide:nicotinic acid ratio in the adipose tissues of 5A-1MQ-treated DIO mice 13