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The Phase 2b OPTIONS trial 536 obese subjects, randomized to receive 0.25, 0.5, or 1 mg/day oral AOD-9604 or placebo over 24 weeks failed to demonstrate statistically significant weight loss at any dose tested
Several factors may affect how the body responds to AOD-9604
Physical activity increases blood flow to the working muscles, which can accelerate absorption of subcutaneously injected medication in ways that are unpredictable
Inositol for the prevention of gestational diabetes: a systematic review and meta-analysis of randomized controlled trials