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Dosing is individualized, but a typical protocol titrates from a starting dose up to a target dose over 2 to 4 weeks, injected 5 days on and 2 days off, in defined cycles with scheduled breaks between them

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Furthermore, AMPK activity influences the intracellular iron metabolism and ferroptosis by decreasing the uptake of iron ions by intestinal epithelial cells, as well as the storage and release of iron ions by the liver (37)

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