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As of 2022, GLP-1RAs have been recommended as first-line treatments, along with SGLT-2 inhibitors, for patients with T2DM and cardiovascular disease in American Diabetes Associations Standards of Medical Care in Diabetes (248, 249)
The regulation of GLP-1 secretion both in humans [44] and at the cellular level [45] has been studied but, except for the finding that ingestion of whey protein as a preload 30 min before a meal augments the GLP-1 response, with clinical benefits for type 2 diabetes [46], it has been difficult to translate the knowledge gained into clinically relevant formulations
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Liver Conditions: Used in alcohol-related liver disease, liver cirrhosis, and liver damage linked to HIV or hepatitis C
It is projected that the rise of these drugs will be driven by increased penetration in primary care facilities, availability via pharmacies, obesity treatment through telehealth, and higher consumer demand for more accessible forms of treatment
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