Avoid very sweet drinks that add sugar and calories on top of the alcohol
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Given the substantial differences between mice and humans in both microbiome composition and immune function, integration of human datasets and model systems will be essential to facilitate this translation
Although the condition is considered to be largely benign, MAFLD can progress to a more severe disease called metabolic dysfunction-associated steatohepatitis (MASH
(103) have recently demonstrated that, compared with the nonpathological variant, the NAFLD-linked PNPLA3 variant more effectively competes with the major intracellular TAG lipase ATGL for binding with the coactivator CGI-58, thereby sequestering CGI-58 and preventing the activation of ATGL
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