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The barley transcription factor HvMYB1 is a positive regulator of drought tolerance
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In the Phase 2 obesity trial, the 12 mg weekly dose produced a mean weight reduction of about 24.2% at 48 weeks ( Jastreboff et al., NEJM 2023 ) the largest figure reported for any single agent in the incretin class at the time
Outcome measures include biomechanical testing (load to failure, stiffness), histological scoring (collagen organization, fibroblast density), and functional assessment (gait analysis, range of motion)
16S rRNA sequencing In 16S rRNA gene sequencing, the sequences were output from 16S rRNA variable region V3-V4 through Illumina Miseq sequencing platform and demultiplexed by Illumina CAVASA 1.8 that obtained from Biotools Co., Ltd