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[2,6] Also involve them for rapid regain, significant distress, binge patterns, loss-of-control eating, adverse effects particularly persistent gastrointestinal symptoms, or if peri-operative planning is relevant

Cardiovascular effects are characterized and mild: a transient systolic blood pressure increase of approximately 6 mmHg peaking at 2 to 4 hours post-dose, with a heart rate reduction of up to 5 beats per minute

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However, it may exacerbate symptoms in individuals who are already lactose intolerant, as it contains lactose as an inactive ingredient