[41] [42] Functional vitamin B 12 deficiency can also develop with heavy regular use of nitrous oxide N 2 O, also known as "laughing gas", by oxidizing the cobalt atom and inactivating the vitamin
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In this context, analytical methods such as HPLC peptide analysis and LC-MS verification can help evaluate purity, identity, molecular characteristics, and research material consistency
Search strings used for each database are presented in Supplementary Table S2