Yes, switching between peptides is possible and sometimes beneficial
In their post hoc analysis of data from subjects in the SURPASS program, the investigators compared changes in mean HbA1c (blood sugar), body weight, and cardiometabolic markers including waist circumference , lipids, and blood pressure in subjects with early-onset type 2 diabetes (N=873, 20.5%) vs later-onset type 2 diabetes (N=3394, 79.5%)
References Alisi A, Piemonte F, Pastore A, Panera N, Passarelli C, Tozzi G, Petrini S, Pietrobattista A, Bottazzo GF, Nobili V (2009) Glutathionylation of p65NF-kappaB correlates with proliferating/apoptotic hepatoma cells exposed to pro- and anti-oxidants
36,37 It is thought to negatively impact reproductive function by increasing inflammation, insulin resistance, and oxidative stress
The SURMOUNT-4 trial showed that 82.5% of people who stopped regained at least 25% of their lost weight within a year
Retatrutide dosage starts with 1 mg once weekly, injected subcutaneously