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The down-regulation of PGC-1 further inhibits the expression of downstream factors such as nuclear respiratory factor 1 and mitochondrial transcription factor A, thereby damaging the mitochondrial biosynthesis process, which is often accompanied by an increase in the oxidative stress levels [31]
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M., Rothstein, M
Semaglutide is a once-weekly injection used for adults who are overweight and/or have medical-related problems that are worsened because of their obesity
Thiebaud N, Llewellyn-Smith IJ, Gribble F, et al
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