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Front Cell Infect Microbiol (2024) 14:1348713

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

Furthermore, redox dysregulation may act as a double-edged sword, inducing a cascade of cellular events that lead to neurodegeneration and simultaneously inactivating protective thiols such as PDI by post-translational modifications

To manage nausea, try eating smaller, more frequent meals

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