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Free Radic Biol Med 48:493498 Lee JY, Sohn KH, Rhee SH, Hwang D (2001) Saturated fatty acids but not unsaturated fatty acids induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4

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Peptide clearance does not scale identically across species, and the animal work used anesthetized preparations and doses far above the human protocol