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Funcin metablica de la l-carnitina: formacin de acetil-carnitina La funcin cataltica mejora la eficiencia de la produccin energtica, mientras que la funcin metablica (o funcin buffer) permite: a) eliminar de la clula los grupos acil, potencialmente txicos , b) mantener un adecuado ratio acetil CoA/CoA libre , c) regular la gluconeneognesis, la sntesis de cidos grasos, triglicridos y cuerpos cetnicos

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1 Introduction Neurodegenerative diseases are irreversible disorders of the nervous system caused by progressive loss of neurons in the brain and spinal cord ( In recent decades, studies have identified several key factors contributing to neurodegeneration, including inflammation, aging, oxidative stress, and genetic mutations ( Over the past few decades, multiple modes of cell death have been defined