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Radiat Oncol 7:152, 2012

These observations indicate that DMFs activation of NRF2 originates not only from inducing NRF2 in the cytoplasm but also from inhibiting the NRF2 repressor in the nucleus

The different nature of these residues is suggested to be responsible for the differences in catalytic properties of mesophilic and extremophilic GGTs ( FIGURE 5 Recent crystallographic studies on L-Glu-bound BlGGT demonstrated that its active site channel constitutes two extensive pockets at the intersubunit interface lined mainly by hydrophobic residues

Edwards, M

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