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From a biochemical standpoint, the rationale is sound
Fully independent peer-reviewed replication of Dihexas specific potency claims (including the widely cited 7 orders of magnitude more potent than BDNF figure from the original work) is limited
The condition is unilateral, affecting one eye at a time
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It can significantly reduce ciclosporin absorption (coadministration is not recommended), requires separation from levothyroxine by at least 4 hours (with TSH monitoring), may enhance the effect of warfarin requiring INR monitoring, and caution is needed with antiepileptics and amiodarone
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