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ZhaoXWangMWenZLuZCuiLFuCet al

One clinical trial showed that ipamorelin administered to healthy volunteers produced dose-dependent, pulsatile increases in growth hormone concentrations with predictable pharmacokinetics and without serious adverse effects, establishing its ability to stimulate GH release

Chen Y, Lin YC, Kuo TW, Knight ZA

Therefore, these pieces of evidence suggest the development of GIP-antagonists for the treatment of BW gain and obesity

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