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10.1042/bj20110544 Biochem

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According to the Institute for Health Metrics and Evaluation, metabolic disorders and high body mass index contributed to more than 5 million global deaths annually

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A 2019 review in the Journal of Physiology noted that "IGF-1 signalling and mechanical loading converge on mTORC1 to regulate skeletal muscle protein synthesis, and the relative contribution of each remains an active area of investigation" [6]

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