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Thus, the inability to account for inhibition of IGF-2 binding to the IGF-1R is an important limitation in this study, which should be considered when assessing outcomes from human trials using IGF-1R mAbs

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Both stimulate collagen production, but through fundamentally different mechanisms and understanding these differences is key to selecting the right compound for specific research objectives

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doi: 10.3233/JPD-130230 93 MeiserJWeindlDHillerK