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The comparative results of the most promising compound from the publication, compound 24 , benchmarked against epacadostat showed significantly higher ratio of [AUC glucuronide]/[AUC parent]

The following framework draws on copper metabolism principles from the American Association for the Study of Liver Diseases (AASLD) Wilson disease guidelines [13] and general wound-care monitoring standards from the Wound Healing Society [14]

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The best results come from consistent treatmentsusually once or twice a week for 8-12 weeks, then maintenance treatments monthly

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