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Melanoma Res 2013

Specifically, at the highest dose tested (12 mg weekly), nausea occurred in roughly 45 to 60 percent of participants

As confirmatory secondary endpoints, the team assessed whether participants attained at least 10%, 15%, and 20% bodyweight reduction till week 68 and reported any physical function outcomes, which included absolute body weight, BMI, waist circumference, blood pressure, glucose homeostasis changes, and glycaemic status

Sometimes, and it varies widely

Secondary parameters were fasting glucose and total lean mass

The most likely route to access in the UK, once approved, will be through regulated online pharmacies and weight loss clinics initially privately, before any consideration of NHS funding