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It is synthesized in the liver and kidneys

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GLP-1 agonists1 help the pancreas release insulin, reduce excess glucagon (a hormone that raises blood sugar) , slow down digestion, and signal the brain to increase fullness and reduce hunger

However, a one-year randomized, double-blind, placebo-controlled trial in 253 elderly (65 years) adults with elevated homocysteine levels found that B vitamin supplementation (1,000 g/day of folate, 10 mg/day of vitamin B 6 , and 500 g/day of vitamin B 12 ) did not improve measures of cognitive function, including memory, despite lowering homocysteine levels (116)

It is the body's primary intracellular antioxidant, operating in both the cytosol and mitochondria, and is directly responsible for regenerating Vitamin C, Vitamin E, and alpha lipoic acid