Blood glucose readings are consistently outside your target range whether persistently high (hyperglycaemia) or frequently low, this indicates your current treatment is not optimally controlling your diabetes
That same appetite suppression that's helping you lose weight is also making it really hard to eat enough protein - and protein is the thing standing between you and losing muscle along with fat
Raul V
Additional trials are also underway in participants with type 1 diabetes targeting diverse pathways including oxidative stress, using nicotinamide adenine dinucleotide phosphate oxidase (Nox)-1/4 inhibitors, and the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, using bardoxolone (NCT03366337, NCT03550443) [84, 85]
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Practical supports are the ones that let you detect change early: Frequent weight checks Simple glucose logs if relevant Short follow-up visits in the first few weeks Clinicians may discuss alternative options such as different GLP-1 agents or combination therapies if weight or glucose control slips
