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It helps transport fatty acids into the mitochondria, where they are burned as fuel
Indeed, inflammaging is associated with cell ROS over-production leading to oxidation/damage of cellular components, enhanced inflammation, and activation of cell death pathways
Meta-analysis of the efficacy of amifostine in the prevention of cisplatin ototoxicity
This cascade includes phosphorylation and inhibition of pyruvate dehydrogenase by PDK1, thereby obstructing pyruvate entry into the TCA cycle (35)
The overexpression level of the recombinant protein, GshF, seem to be affected by the deletion of these genes of the host strain
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