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Typical dosages range from: 200 mcg to 500 mcg per day for minor injuries Up to 1,000 mcg per day for more serious cases Duration of therapy generally spans 2 to 4 weeks, though some protocols extend longer depending on the severity of the condition

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Acute sciatica from a recent disc herniation often responds within 4-8 weeks of consistent care

The lower dose (100 mg vs 500 mg in standard reduced products) reflects the theoretically higher bioavailability of the acetylated form

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