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Figure 3 Tumor Necrosis Factor Both TNF and IL-6 are correlated with the body mass index (BMI), and TNF is known to play a role in obesity and in particular in the insulin resistance and diabetes that often accompany obesity ( Tumor necrosis factor is a therapeutic target in several diseases and anti-TNF treatment is successfully applied in rheumatoid arthritis, psoriasis, ankylosing spondylitis, and IBD
Por otro lado, el efecto antihiperglucemiante de los inhibidores del cotransportador sodio-glucosa tipo 2 (iSGLT2) disminuye a medida que lo hace el filtrado glomerular (FG), con FGe 15ml/min/1,73m2)78
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