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This pattern suggests that oral bioavailability may vary significantly between individuals and that systemic effects require adequate absorption that not everyone achieves

Patients should avoid injecting into areas with skin abnormalities, including active inflammation, infection, rashes, scars, or areas with significant bruising or hardened tissue from previous injections

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The vehicle group did not differ in locomotor activity between baseline and post-injection (Bonferroni post-hoc analysis, p = NS