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All authors contributed to the interpretation of the study and to further drafts

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Genes associated to metal and oxidative stress response were up-regulated while genes involved to pathogens and hormonal stimuli response were down-regulated

Sulforaphane, derived from the corresponding glucoraphanin glucosinolate found in abundance in cruciferous vegetables, has recently been recognised as an effective neuroprotective compound

Lentivirus was transfected into tenocytes to induce GPX3 overexpression, and pefloxacin (100 M, 24 h) was administered (Figure 7A)