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Thats because vitamin B12 aids in the production of the neurotransmitters that are responsible for regulating mood and cognitive function

This is called the initial loading phase

A pharmacokinetic study in rats found that oral administration produced substantial plasma concentrations, with a maximum concentration of 2252 ng/mL and an elimination half-life of approximately 6.9 hours

Patients should be counseled never to administer extra doses to make up for missed doses, as this could increase the risk of adverse effects without providing additional therapeutic benefit

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The researchers weren't sure why