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In another study, 2 days after a regimen of repeated bi-daily 15 mg/kg cocaine treatments, over 5 days, withdrawing rats had decreased TH-immunoreactive varicosities in the nucleus accumbens core, while these increased in the shell at 14 days post-withdrawal, suggesting the involvement of these changes in behavioral sensitization [36]
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Final Thoughts Switching from semaglutide to tirzepatide is one of the more common transitions in GLP-1 therapyand for some people, its a logical next step when progress stalls or goals shift
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