b12 500 mcg injection Bi-12® Vitamin B12 Injection at a

hospitalization required Maintenance of Remission: Immunomodulators (azathioprine, 6-MP, methotrexate) for steroid-dependent or frequently-relapsing disease Biologic monotherapy or combination therapy (biologic + immunomodulator) for moderate-to-severe disease Step-up or top-down approach based on disease severity, patient risk factors, and prior therapy Biologic Therapy Targets: TNF-: Infliximab (IV), adalimumab (SC), certolizumab pegol (SC) IL-12/23: Ustekinumab (IV induction, SC maintenance) Integrin: Vedolizumab (IV) IL-23: Risankizumab (IV induction, SC maintenance) JAK inhibition: Upadacitinib (oral) Surgical Management Surgery is indicated in approximately 7080% of patients with Crohns disease over their lifetime, per StatPearls

This injection is typically used to treat and prevent vitamin B12 deficiency, which can lead to anemia, nerve damage, and other health complications

Methionine Methionine is an essential amino acid found in lean meats, dairy, eggs, and nuts

Nat Chem Biol

Unlike cyanocobalamin, hydroxocobalamin offers sustained release, ensuring longer-lasting benefits for those with B12 deficiency, fatigue, or general wellness concerns

(Roll the vial between your hands gently to mix, do not shake