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Glutathione is an investigational research material commonly evaluated in laboratory models involving glutathione-dependent antioxidant systems, oxidative stress models, and cellular detoxification pathway research

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Studies have shown that the gut microbiota not only directly affects the production of glucocorticoids and immune mediators, such as tumor necrosis factor- (TNF-), interleukin-1 (IL-1), and IL-6, but also further stimulates HPA axis activity through these mediators (112)

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