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[6] [7] These medications work by mimicking naturally occurring hormones that regulate blood glucose and appetite

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Obesity Prevention Source (2024)

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More recent studies suggest that the blood concentration of trimethylamine N-oxide (TMAO), generated from trimethylamine-containing nutrients like dietary choline, rather than that of choline, might influence the risk of cardiovascular events (see Safety)

Carbo-loading/phasing: if an athlete is carbohydrate loading or having low and high-carbohydrate periods in their day and training week, the times when carbohydrates are ingested (such as a high-carb recovery meal after a long session) are ideal times to include the 1500-3000mg of carnitine