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In the gutkidney axis, barrier disruption may accelerate systemic toxin exposure and promote renal damage [356, 358], while in the gutheart axis, it may contribute to endothelial dysfunction and chronic vascular inflammation [359]
The development of novel drug delivery systems or formulations is also essential to improve patient compliance and reduce gastrointestinal adverse effects
10.1016/S0753-3322(03)00043-X
In rats with streptozotocin-induced diabetes, liraglutide was shown to directly protect the rats against oxidative stress through the inhibition of NAD(P)H oxidases (11)
A previous study 286 revealed not only that p53 can modulate liver fibrosis by altering CTGF expression but also that the p53/CTGF pathway may be a new target in the treatment of liver fibrosis
Mt s tc dng ph nh ghi nhn bao gm: y bng, chua v mi v kh chu trong ming
