The problem with oral B12 is that the same stomach acids responsible for breaking down food also break down supplements the body can only absorb a small fraction of what a pill contains
This includes severe malabsorption or when injections in the muscle are not possible
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Vitamin B12 deficiency is the dominant nutritional cause of hyperhomocysteinemia in a folic acid-fortified population
Common injection sites include the abdomen (2 inches from navel), upper thighs, or upper arms
The injection is providing you with the necessary B vitamins regardless of your food intake, which is helpful especially if you have trouble eating a balanced diet (due to illness or other reasons)