how much weight can i lose on a glp 1 loss maintenance after discontinuing GLP-1 : r/Zepbound GLP-1 Injection Results | Weight

Knudsen LB, Nielsen PF, Huusfeldt PO et al

Key pharmacological effects include: Glucose-dependent insulin secretion Enhanced pancreatic beta-cell insulin release only when blood glucose is elevated, reducing hypoglycemia risk Suppression of glucagon secretion Decreased hepatic glucose production from pancreatic alpha cells Delayed gastric emptying Slowed movement of food from the stomach to the small intestine Central appetite regulation Reduced hunger and increased satiety through hypothalamic pathways The delayed gastric emptying effect is particularly significant and represents both a therapeutic mechanism and a potential source of adverse effects

* This statement has not been evaluated by the Food & Drug Administration

PMID 29794051

Sublingual administration achieves 55% penetration after 10 minutes and approximately 70% after 30 minutes through oral epithelium

They are permitted under specific conditions, but they are not FDA approved products, and they cannot be marketed as equivalent to the branded drugs