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doi:10.1155/2021/9458587

Concurrently, the emergence of molecularly intelligent photosensitizers that change their photophysical or chemical behavior in response to lesion-specific cues (pH, enzymes, redox) exemplifies how analyte-sensing functionality can be built directly into imaging-therapeutic agents

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14 In contrast, studies report that administering GABA-A receptor antagonists to rodents in the striatum and intra-cortex induces twitching symptoms, which can be alleviated by the administration of GABA-A receptor agonists