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Doses Per Vial Vial duration varies by dose escalation phase: 3mg vial: At 0.25mg/week = 12 weeks At 0.5mg/week = 6 weeks At 1mg/week = 3 weeks At 2.4mg/week = 1.25 weeks 5mg vial: At 0.25mg/week = 20 weeks At 0.5mg/week = 10 weeks At 1mg/week = 5 weeks At 1.7mg/week = ~3 weeks At 2.4mg/week = ~2 weeks A 5mg vial can cover the entire first 4 months of a slow escalation protocol starting at 0.25mg

During the preparation of this work, the author(s) used ChatGPT to correct the grammar, language and used Google Gemini to create Figure 1

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