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mitochondrial studies may compare MOTS-c, SS-31 (Elamipretide) and NAD+ Injectable

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As detailed in later sections, the DMRS spectra of one WT mouse was excluded due to failure in data processing, the fMRI data from one GLP-1R KO mouse was excluded due to being an outlier, and one GLP-1R KO mouse died during PET image acquisition

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According to the Wegovy Summary of Product Characteristics (SmPC) , if Wegovy has been discontinued for more than two consecutive doses during the dose escalation phase, or more than two consecutive doses at any maintenance dose , treatment should generally be reinitiated at a lower dose (often 0.25 mg once weekly) and re-titrated according to clinical judgement

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