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doi: 10.1038/srep27524 49

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Ba-Carneiro JL, Akemi Guirao Sumida I, Gallon M, Zaleski T, Boia-Ferreira M and Bridi Cavassin F (2022) Sertraline repositioning: An overview of its potential use as a chemotherapeutic agent after four decades of tumor reversal studies

Acta 1839 (12), 14541462

MOTS-c modulates the FOXO transcription factors and regulates cellular senescence, the state in which aged or damaged cells stop dividing but refuse to die, instead secreting a cocktail of inflammatory signals known as the senescence-associated secretory phenotype (SASP)

To ensure autophagic activation by PFOS, we generated a stable GFP-LC3B clone of RTCs and counted LC3 puncta at 424 h of PFOS treatment (Fig