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Honda et al
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Sermorelin and Tesamorelin both act on the same GHRH receptor, but Tesamorelin is more clinically validated for the visceral-fat-reduction indication and produces more consistent reductions in deep abdominal fat in studies
Combined with the systemic anti-aging effects on gene expression, this peptide delivers value beyond just skin appearance
The majority of the published literature examines each compound independently, and the synergy hypothesis, while mechanistically well-supported, has not yet been the subject of large-scale controlled studies
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