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Here's what happens when caloric intake drops too low for too long on a GLP-1: Muscle loss

In this extension, participants continued to lose weight, reaching a maximum tolerated dose of either 9 mg or 12 mg

These effects tend to diminish within a few weeks of treatment

Are there any long-term concerns I should be aware of

Supplementing with it can reduce the frequency and severity of migraines by improving energy production in brain cells and reducing inflammation

When patients stayed on treatment for the full duration, that number climbed to 16.6%, essentially matching the weight loss performance of injectable WEGOVY 2.4 mg